Capsaicin, a TRPV1 Ligand, Suppresses Bone Resorption by Inhibiting the Prostaglandin E Production of Osteoblasts, and Attenuates the Inflammatory Bone Loss Induced by Lipopolysaccharide

Capsaicin, a transient receptor potential vanilloid type 1 (TRPV1) ligand, regulates nerve-related pain-sensitive signals, inflammation, and cancer growth. Capsaicin suppresses interleukin-1-induced osteoclast differentiation, but its roles in bone tissues and bone diseases are not known. This study...

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Detalhes bibliográficos
Main Authors: Kobayashi, Megumi, Watanabe, Kenta, Yokoyama, Satoshi, Matsumoto, Chiho, Hirata, Michiko, Tominari, Tsukasa, Inada, Masaki, Miyaura, Chisato
Formato: Artigo
Idioma:Inglês
Publicado em: International Scholarly Research Network 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324930/
https://ncbi.nlm.nih.gov/pubmed/22548186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5402/2012/439860
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