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Extracellular polyphosphate signals through Ras and Akt to prime Dictyostelium discoideum cells for development

Linear chains of five to hundreds of phosphates called polyphosphate are found in organisms ranging from bacteria to humans, but their function is poorly understood. In Dictyostelium discoideum, polyphosphate is used as a secreted signal that inhibits cytokinesis in an autocrine negative feedback lo...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Suess, Patrick M., Watson, Jacob, Chen, Wensheng, Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536921/
https://ncbi.nlm.nih.gov/pubmed/28584190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.203372
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