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Extracellular Polyphosphate Inhibits Proliferation in an Autocrine Negative Feedback Loop in Dictyostelium discoideum

Polyphosphate is a polymer of phosphate residues linked by high energy phosphoanhydride bonds. Despite being highly conserved throughout nature, its function is poorly understood. Here we show that Dictyostelium cells accumulate extracellular polyphosphate, and this acts to inhibit proliferation at...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Suess, Patrick M., Gomer, Richard H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025707/
https://ncbi.nlm.nih.gov/pubmed/27519410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.737825
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