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VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels

Visual information is relayed from the eye to the brain via retinal ganglion cell (RGC) axons. Mice lacking NRP1 or NRP1-binding VEGF-A isoforms have defective RGC axon organisation alongside brain vascular defects. It is not known whether axonal defects are caused exclusively by defective VEGF-A si...

詳細記述

保存先:
書誌詳細
出版年:Development
主要な著者: Erskine, Lynda, François, Urielle, Denti, Laura, Joyce, Andy, Tillo, Miguel, Bruce, Freyja, Vargesson, Neil, Ruhrberg, Christiana
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists Ltd 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536872/
https://ncbi.nlm.nih.gov/pubmed/28676569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.151621
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