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Downregulation of SMC1A inhibits growth and increases apoptosis and chemosensitivity of colorectal cancer cells

OBJECTIVE: The structural maintenance of chromosomes (SMC) 1A protein is a component of the cohesin multiprotein complex that is essential for sister chromatid cohesion. SMC1A gene mutations have been reported in colorectal cancer. This study aimed to investigate the role of SMC1A gene expression in...

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Detalles Bibliográficos
Publicado en:J Int Med Res
Main Authors: Li, Jin, Feng, Wanting, Chen, Longbang, He, Jingdong
Formato: Artigo
Idioma:Inglês
Publicado: SAGE Publications 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536575/
https://ncbi.nlm.nih.gov/pubmed/26637483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060515600188
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