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Downregulation of SMC1A inhibits growth and increases apoptosis and chemosensitivity of colorectal cancer cells

OBJECTIVE: The structural maintenance of chromosomes (SMC) 1A protein is a component of the cohesin multiprotein complex that is essential for sister chromatid cohesion. SMC1A gene mutations have been reported in colorectal cancer. This study aimed to investigate the role of SMC1A gene expression in...

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Détails bibliographiques
Publié dans:J Int Med Res
Auteurs principaux: Li, Jin, Feng, Wanting, Chen, Longbang, He, Jingdong
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536575/
https://ncbi.nlm.nih.gov/pubmed/26637483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0300060515600188
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