Origins of lymphatic and distant metastases in human colorectal cancer

The spread of cancer cells from primary tumors to regional lymph nodes is often associated with reduced survival. One prevailing model to explain this association posits that fatal, distant metastases are seeded by lymph node metastases. This view provides a mechanistic basis for the TNM staging sys...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Naxerova, Kamila, Reiter, Johannes G., Brachtel, Elena, Lennerz, Jochen, Van de Wetering, Marc, Rowan, Andrew, Cai, Tianxi, Clevers, Hans, Swanton, Charles, Nowak, Martin A., Elledge, Stephen J., Jain, Rakesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536201/
https://ncbi.nlm.nih.gov/pubmed/28684519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aai8515
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