Imatinib Triggers Phagolysosome Acidification and Antimicrobial Activity against Mycobacterium bovis Bacille Calmette–Guérin in Glucocorticoid-Treated Human Macrophages

Glucocorticoids are extensively used to treat inflammatory diseases; however, their chronic intake increases the risk for mycobacterial infections. Meanwhile, the effects of glucocorticoids on innate host responses are incompletely understood. In this study, we investigated the direct effects of glu...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Steiger, Julia, Stephan, Alexander, Inkeles, Megan S., Realegeno, Susan, Bruns, Heiko, Kröll, Philipp, de Castro Kroner, Juliana, Sommer, Andrea, Batinica, Marina, Pitzler, Lena, Kalscheuer, Rainer, Hartmann, Pia, Plum, Georg, Stenger, Steffen, Pellegrini, Matteo, Brachvogel, Bent, Modlin, Robert L., Fabri, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5536119/
https://ncbi.nlm.nih.gov/pubmed/27233968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1502407
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