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Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach

Adenosine monophosphate-activated protein kinase (AMPK) plays a critical role in the regulation of energy metabolism and has been targeted for drug development of therapeutic intervention in Type II diabetes and related diseases. Recently, there has been renewed interest in the development of direct...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Huang, Tonghui, Sun, Jie, Zhou, Shanshan, Gao, Jian, Liu, Yi
Format: Artigo
Langue:Inglês
Publié: MDPI 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535900/
https://ncbi.nlm.nih.gov/pubmed/28665353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071408
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