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Novel Thiazolo[5,4-b]phenothiazine Derivatives: Synthesis, Structural Characterization, and In Vitro Evaluation of Antiproliferative Activity against Human Leukaemia

The molecular frame of the reported series of new polyheterocyclic compounds was intended to combine the potent phenothiazine and benzothiazole pharmacophoric units. The synthetic strategy applied was based on oxidative cyclization of N-(phenothiazin-3-yl)-thioamides and it was validated by the prep...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Brem, Balazs, Gal, Emese, Găină, Luiza, Silaghi-Dumitrescu, Luminiţa, Fischer-Fodor, Eva, Tomuleasa, Ciprian Ionuţ, Grozav, Adriana, Zaharia, Valentin, Filip, Lorena, Cristea, Castelia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535858/
https://ncbi.nlm.nih.gov/pubmed/28672876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071365
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