Novel Thiazolo[5,4-b]phenothiazine Derivatives: Synthesis, Structural Characterization, and In Vitro Evaluation of Antiproliferative Activity against Human Leukaemia

The molecular frame of the reported series of new polyheterocyclic compounds was intended to combine the potent phenothiazine and benzothiazole pharmacophoric units. The synthetic strategy applied was based on oxidative cyclization of N-(phenothiazin-3-yl)-thioamides and it was validated by the prep...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Brem, Balazs, Gal, Emese, Găină, Luiza, Silaghi-Dumitrescu, Luminiţa, Fischer-Fodor, Eva, Tomuleasa, Ciprian Ionuţ, Grozav, Adriana, Zaharia, Valentin, Filip, Lorena, Cristea, Castelia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535858/
https://ncbi.nlm.nih.gov/pubmed/28672876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18071365
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