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mTORC2-IRF4 mediated metabolic reprograming is essential for macrophage alternative activation

Changes in metabolism can be initiated in response to signals received from other cells. An example of this is provided by macrophages that have been stimulated by IL-4 to become alternatively/M2 activated. In these cells, fatty acid oxidation is increased and this is critical for M2 activation. Com...

詳細記述

保存先:
書誌詳細
出版年:Immunity
主要な著者: Huang, Stanley Ching-Cheng, Smith, Amber M., Everts, Bart, Colonna, Marco, Pearce, Erika L., Schilling, Joel D., Pearce, Edward J.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535820/
https://ncbi.nlm.nih.gov/pubmed/27760338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.09.016
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