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mTORC2-IRF4 mediated metabolic reprograming is essential for macrophage alternative activation
Changes in metabolism can be initiated in response to signals received from other cells. An example of this is provided by macrophages that have been stimulated by IL-4 to become alternatively/M2 activated. In these cells, fatty acid oxidation is increased and this is critical for M2 activation. Com...
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| 出版年: | Immunity |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535820/ https://ncbi.nlm.nih.gov/pubmed/27760338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.09.016 |
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