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Restructuring of an RNA polymerase holoenzyme elongation complex by lambdoid phage Q proteins

The structure of an intermediate in the initiation to elongation transition of Escherichia coli RNA polymerase has been visualized through region-specific DNA cleavage by the hydroxyl radical reagent FeBABE. FeBABE was tethered to specific sites of the σ(70) subunit and incorporated into two special...

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Autors principals: Marr, Michael T., Datwyler, Saul A., Meares, Claude F., Roberts, Jeffrey W.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC55358/
https://ncbi.nlm.nih.gov/pubmed/11481468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161253298
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