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The transcriptional repressor GATAD2B mediates progesterone receptor suppression of myometrial contractile gene expression

The mechanisms whereby progesterone (P(4)), acting via the progesterone receptor (PR), inhibits proinflammatory/contractile gene expression during pregnancy are incompletely defined. Using immortalized human myometrial (hTERT-HM) cells stably expressing wild-type PR-A or PR-B (PR(WT)), we found that...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Chen, Chien-Cheng, Montalbano, Alina P., Hussain, Imran, Lee, Wan-Ru, Mendelson, Carole R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5535031/
https://ncbi.nlm.nih.gov/pubmed/28576827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.791350
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