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The H3 loop of antibodies shows unique structural characteristics
The H3 loop in the Complementarity Determining Region of antibodies plays a key role in their ability to bind the diverse space of potential antigens. It is also exceptionally difficult to model computationally causing a significant hurdle for in silico development of antibody biotherapeutics. In th...
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| 發表在: | Proteins |
|---|---|
| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
John Wiley and Sons Inc.
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5535007/ https://ncbi.nlm.nih.gov/pubmed/28342222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25291 |
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