Non-methylated CpG-rich islands at the human alpha-globin locus: implications for evolution of the alpha-globin pseudogene.

We have analysed CpG frequency and CpG methylation across part of the human alpha-globin locus. Clusters of CpG at the alpha 1 and alpha 2 genes resemble the 'HpaII tiny fragment (HTF) islands' that are characteristic of mammalian 'housekeeping' genes: CpG frequency is not suppressed; testable CpGs...

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Pubblicato in:	EMBO J
Autori principali:	Bird, A P, Taggart, M H, Nicholls, R D, Higgs, D R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3595568/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04851.x
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