T cell neoepitope discovery in colorectal cancer by high throughput profiling of somatic mutations in expressed genes

OBJECTIVE: Patient-specific (unique) tumour antigens, encoded by somatically mutated cancer genes, generate neoepitopes that are implicated in the induction of tumour-controlling T cell responses. Recent advancements in massive DNA sequencing combined with robust T cell epitope predictions have allo...

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Detaylı Bibliyografya
Yayımlandı:Gut
Asıl Yazarlar: Mennonna, Daniele, Maccalli, Cristina, Romano, Michele C, Garavaglia, Claudio, Capocefalo, Filippo, Bordoni, Roberta, Severgnini, Marco, De Bellis, Gianluca, Sidney, John, Sette, Alessandro, Gori, Alessandro, Longhi, Renato, Braga, Marco, Ghirardelli, Luca, Baldari, Ludovica, Orsenigo, Elena, Albarello, Luca, Zino, Elisabetta, Fleischhauer, Katharina, Mazzola, Gina, Ferrero, Norma, Amoroso, Antonio, Casorati, Giulia, Parmiani, Giorgio, Dellabona, Paolo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMJ Publishing Group 2017
Konular:
Colon
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534766/
https://ncbi.nlm.nih.gov/pubmed/26681737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-309453
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