Production of hepatitis B virus in vitro by transient expression of cloned HBV DNA in a hepatoma cell line.

Transfection of human hepatoma cell lines with cloned HBV DNA resulted in the secretion of large amounts of hepatitis B surface antigen (HBsAg) and core-related antigens (HBc/HBeAg) if well-differentiated cell lines were employed. Synthesis of both viral antigens was the highest in cell line HuH-7 a...

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Detalles Bibliográficos
Publicado en:EMBO J
Autores principales: Chang, C M, Jeng, K S, Hu, C P, Lo, S J, Su, T S, Ting, L P, Chou, C K, Han, S H, Pfaff, E, Salfeld, J
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3034605/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04807.x
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