Production of hepatitis B virus in vitro by transient expression of cloned HBV DNA in a hepatoma cell line.

Transfection of human hepatoma cell lines with cloned HBV DNA resulted in the secretion of large amounts of hepatitis B surface antigen (HBsAg) and core-related antigens (HBc/HBeAg) if well-differentiated cell lines were employed. Synthesis of both viral antigens was the highest in cell line HuH-7 a...

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Detalhes bibliográficos
Main Authors: Chang, C M, Jeng, K S, Hu, C P, Lo, S J, Su, T S, Ting, L P, Chou, C K, Han, S H, Pfaff, E, Salfeld, J
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC553450/
https://ncbi.nlm.nih.gov/pubmed/3034605
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