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Endothelial Notch signalling limits angiogenesis via control of artery formation

Angiogenic sprouting needs to be tightly controlled. It has been suggested that the Notch ligand dll4 expressed in leading tip cells restricts angiogenesis by activating Notch signalling in trailing stalk cells. Here, we show using live imaging in zebrafish that activation of Notch signalling is rat...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Hasan, Sana S., Tsaryk, Roman, Lange, Martin, Wisniewski, Laura, Moore, John C., Lawson, Nathan D., Wojciechowska, Karolina, Schnittler, Hans, Siekmann, Arndt F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534340/
https://ncbi.nlm.nih.gov/pubmed/28714969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3574
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