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In vivo plug-and-play: a modular multi-enzyme single-cell catalyst for the asymmetric amination of ketoacids and ketones

BACKGROUND: Transaminases have become a key tool in biocatalysis to introduce the amine functionality into a range of molecules like prochiral α-ketoacids and ketones. However, due to the necessity of shifting the equilibrium towards the product side (depending on the amine donor) an efficient amina...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Farnberger, Judith E., Lorenz, Elisabeth, Richter, Nina, Wendisch, Volker F., Kroutil, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5534079/
https://ncbi.nlm.nih.gov/pubmed/28754115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-017-0750-5
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