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Overexpression of SMC4 activates TGFβ/Smad signaling and promotes aggressive phenotype in glioma cells

Overexpression of structural maintenance of chromosomes 4 (SMC4) has been reported to be involved in tumor cell growth, migration and invasion, and to be correlated with poor prognosis of cancer patient. However, its clinical significance and biological role in glioma remain unknown. Herein, we foun...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Jiang, L, Zhou, J, Zhong, D, Zhou, Y, Zhang, W, Wu, W, Zhao, Z, Wang, W, Xu, W, He, L, Ma, Y, Hu, Y, Li, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533949/
https://ncbi.nlm.nih.gov/pubmed/28287612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2017.8
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