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Newcastle Disease Virus Establishes Persistent Infection in Tumor Cells In Vitro: Contribution of the Cleavage Site of Fusion Protein and Second Sialic Acid Binding Site of Hemagglutinin-Neuraminidase

Newcastle disease virus (NDV) is an oncolytic virus being developed for the treatment of cancer. Following infection of a human ovarian cancer cell line (OVCAR3) with a recombinant low-pathogenic NDV, persistent infection was established in a subset of tumor cells. Persistently infected (PI) cells e...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Rangaswamy, Udaya S., Wang, Weijia, Cheng, Xing, McTamney, Patrick, Carroll, Danielle, Jin, Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533931/
https://ncbi.nlm.nih.gov/pubmed/28592535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00770-17
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