Targeting Oxygen-Sensing Prolyl Hydroxylase for Metformin-Associated Lactic Acidosis Treatment

Metformin is one of the most widely used therapeutics for type 2 diabetes mellitus and also has anticancer and antiaging properties. However, it is known to induce metformin-associated lactic acidosis (MALA), a severe medical condition with poor prognosis, especially in individuals with renal dysfun...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Oyaizu-Toramaru, Tomoko, Suhara, Tomohiro, Hayakawa, Noriyo, Nakamura, Takashi, Kubo, Akiko, Minamishima, Shizuka, Yamaguchi, Kyoji, Hishiki, Takako, Morisaki, Hiroshi, Suematsu, Makoto, Minamishima, Yoji Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533879/
https://ncbi.nlm.nih.gov/pubmed/28606929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00248-17
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