Translational efficiency of polycistronic mRNAs and their utilization to express heterologous genes in mammalian cells.

The translation of polycistronic mRNAs in mammalian cells was studied. Transcription units, constructed to contain one, two or three open reading frames (ORFs), were introduced stably into Chinese hamster ovary cells and transiently into COS monkey cells. The analysis of mRNA levels and protein synt...

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Библиографические подробности

Опубликовано в::	EMBO J
Главные авторы:	Kaufman, R J, Murtha, P, Davies, M V
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Publishing Group 1987
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553375/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3582359/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04737.x
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