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A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment

Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal compartment of the tumor microenvironment. CAFs support multiple aspects of cancer progression, including tumor initiation, invasion, and metastasis. The heterogeneous nature of the stromal microenvironment...

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Detalhes bibliográficos
Publicado no:Sci Rep
Principais autores: Nair, Neha, Calle, Anna Sanchez, Zahra, Maram Hussein, Prieto-Vila, Marta, Oo, Aung Ko Ko, Hurley, Laura, Vaidyanath, Arun, Seno, Akimasa, Masuda, Junko, Iwasaki, Yoshiaki, Tanaka, Hiromi, Kasai, Tomonari, Seno, Masaharu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533745/
https://ncbi.nlm.nih.gov/pubmed/28754894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07144-5
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