A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment

Cancer-associated fibroblasts (CAFs) are one of the most prominent cell types in the stromal compartment of the tumor microenvironment. CAFs support multiple aspects of cancer progression, including tumor initiation, invasion, and metastasis. The heterogeneous nature of the stromal microenvironment...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nair, Neha, Calle, Anna Sanchez, Zahra, Maram Hussein, Prieto-Vila, Marta, Oo, Aung Ko Ko, Hurley, Laura, Vaidyanath, Arun, Seno, Akimasa, Masuda, Junko, Iwasaki, Yoshiaki, Tanaka, Hiromi, Kasai, Tomonari, Seno, Masaharu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533745/
https://ncbi.nlm.nih.gov/pubmed/28754894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07144-5
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