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Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer’s disease

The heterogeneity of Alzheimer’s disease contributes to the high failure rate of prior clinical trials. We analyzed 5-year longitudinal outcomes and biomarker data from 562 subjects with mild cognitive impairment (MCI) from two national studies (ADNI) using a novel multilayer clustering algorithm. T...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Gamberger, Dragan, Lavrač, Nada, Srivatsa, Shantanu, Tanzi, Rudolph E., Doraiswamy, P. Murali
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533731/
https://ncbi.nlm.nih.gov/pubmed/28755001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06624-y
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