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Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer’s disease

The heterogeneity of Alzheimer’s disease contributes to the high failure rate of prior clinical trials. We analyzed 5-year longitudinal outcomes and biomarker data from 562 subjects with mild cognitive impairment (MCI) from two national studies (ADNI) using a novel multilayer clustering algorithm. T...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gamberger, Dragan, Lavrač, Nada, Srivatsa, Shantanu, Tanzi, Rudolph E., Doraiswamy, P. Murali
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533731/
https://ncbi.nlm.nih.gov/pubmed/28755001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06624-y
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