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Identification of clusters of rapid and slow decliners among subjects at risk for Alzheimer’s disease

The heterogeneity of Alzheimer’s disease contributes to the high failure rate of prior clinical trials. We analyzed 5-year longitudinal outcomes and biomarker data from 562 subjects with mild cognitive impairment (MCI) from two national studies (ADNI) using a novel multilayer clustering algorithm. T...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Gamberger, Dragan, Lavrač, Nada, Srivatsa, Shantanu, Tanzi, Rudolph E., Doraiswamy, P. Murali
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533731/
https://ncbi.nlm.nih.gov/pubmed/28755001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06624-y
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