Two-step membrane binding by the bacterial SRP receptor enable efficient and accurate Co-translational protein targeting

The signal recognition particle (SRP) delivers ~30% of the proteome to the eukaryotic endoplasmic reticulum, or the bacterial plasma membrane. The precise mechanism by which the bacterial SRP receptor, FtsY, interacts with and is regulated at the target membrane remain unclear. Here, quantitative an...

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Vydáno v:eLife
Hlavní autoři: Hwang Fu, Yu-Hsien, Huang, William Y C, Shen, Kuang, Groves, Jay T, Miller, Thomas, Shan, Shu-ou
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2017
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533587/
https://ncbi.nlm.nih.gov/pubmed/28753124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.25885
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