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Simulations of knotting of DNA during genome mapping
Genome mapping involves the confinement of long DNA molecules, in excess of 150 kilobase pairs, in nanochannels near the circa 50 nm persistence length of DNA. The fidelity of the map relies on the assumption that the DNA is linearized by channel confinement, which assumes the absence of knots. We h...
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| Pubblicato in: | Biomicrofluidics |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
AIP Publishing LLC
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533507/ https://ncbi.nlm.nih.gov/pubmed/28798853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4979605 |
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