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Modeling the relaxation of internal DNA segments during genome mapping in nanochannels

We have developed a multi-scale model describing the dynamics of internal segments of DNA in nanochannels used for genome mapping. In addition to the channel geometry, the model takes as its inputs the DNA properties in free solution (persistence length, effective width, molecular weight, and segmen...

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Detalhes bibliográficos
Publicado no:Biomicrofluidics
Main Authors: Jain, Aashish, Sheats, Julian, Reifenberger, Jeffrey G., Cao, Han, Dorfman, Kevin D.
Formato: Artigo
Idioma:Inglês
Publicado em: AIP Publishing LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065570/
https://ncbi.nlm.nih.gov/pubmed/27795749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4964927
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