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Modeling the relaxation of internal DNA segments during genome mapping in nanochannels

We have developed a multi-scale model describing the dynamics of internal segments of DNA in nanochannels used for genome mapping. In addition to the channel geometry, the model takes as its inputs the DNA properties in free solution (persistence length, effective width, molecular weight, and segmen...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Biomicrofluidics
Päätekijät: Jain, Aashish, Sheats, Julian, Reifenberger, Jeffrey G., Cao, Han, Dorfman, Kevin D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: AIP Publishing LLC 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5065570/
https://ncbi.nlm.nih.gov/pubmed/27795749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4964927
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