Treatment combining aliskiren with paricalcitol is effective against progressive renal tubulointerstitial fibrosis via dual blockade of intrarenal renin

The aim of this study was to assess any potential additive effects of a treatment combining aliskiren with paricalcitol on reducing renal fibrosis. C57BL/6J mice were treated individually with aliskiren and/or paricalcitol until 7 days after initiation of unilateral ureteral obstruction (UUO).In obs...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Chung, Sungjin, Kim, Soojeong, Kim, Minyoung, Koh, Eun Sil, Shin, Seok Joon, Park, Cheol Whee, Chang, Yoon Sik, Kim, Ho-Shik
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533315/
https://ncbi.nlm.nih.gov/pubmed/28753620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181757
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