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A novel role for p53 in self-tolerance

In this issue of Blood, Rodrigues et al use a conditional knockout mouse model to describe a novel role for p53 in the differentiation and maintenance of medullary thymic epithelial cells (mTECs), tissue-restricted antigen (TRA) expression, and self-tolerance.(1)

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Dades bibliogràfiques
Publicat a:Blood
Autors principals: Larsen, Brian M., Bhandoola, Avinash
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5533205/
https://ncbi.nlm.nih.gov/pubmed/28751355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-06-789115
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