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p53 at the crossroads of MPN treatment
In this issue of Blood, Lu et al describe the cooperation between an orally bioavailable mouse double minute 2 (MDM2) antagonist (RG7112) and the pegylated interferon α (Peg-IFNα 2a) to target JAK2V617F hematopoietic progenitors and stem cells. Their work provides a rationale for the treatment of pa...
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| Main Author: | |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society of Hematology
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4118478/ https://ncbi.nlm.nih.gov/pubmed/25082860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-06-579623 |
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