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Binge alcohol alters PNPLA3 levels in liver through epigenetic mechanism involving histone H3 acetylation
The human PNPLA3 (patatin-like phospholipase domain-containing 3) gene codes for a protein which is highly expressed in adipose tissue and liver, and is implicated in lipid homeostasis. While PNPLA3 protein contains regions homologous to functional lipolytic proteins, the regulation of its tissue ex...
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| Publié dans: | Alcohol |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5533086/ https://ncbi.nlm.nih.gov/pubmed/28433418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2017.01.009 |
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