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Binge Alcohol Is More Injurious to Liver in Female than in Male Rats: Histopathological, Pharmacologic, and Epigenetic Profiles

Binge alcohol consumption is a health problem, but differences between the sexes remain poorly defined. We have examined the in vivo effects of three acute, repeat binge alcohol administration on the liver in male and female rats. Sprague-Dawley rats were gavaged with alcohol (5 g/kg body weight) th...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Shukla, Shivendra D., Restrepo, Ricardo, Aroor, Annayya R., Liu, Xuanyou, Lim, Robert W., Franke, Jacob D., Ford, David A., Korthuis, Ronald J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6695503/
https://ncbi.nlm.nih.gov/pubmed/31262967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.258871
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