Inhibition of Notch Signaling in Glioblastoma Targets Cancer Stem Cells via an Endothelial Cell Intermediate

Glioblastoma multiforme (GBM) is a highly heterogeneous malignant tumor. Recent data suggests the presence of a hierarchical organization within the GBM cell population that involves cancer cells with stem-like behavior, capable of repopulating the tumor and contributing to its resistance to therapy...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Hovinga, Koos E., Shimizu, Fumiko, Wang, Rong, Panagiotakos, Georgia, Van Der Heijden, Maartje, Moayedpardazi, Hamideh, Correia, Ana Sofia, Soulet, Denis, Major, Tamara, Menon, Jayanthi, Tabar, Viviane
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532884/
https://ncbi.nlm.nih.gov/pubmed/20506127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.429
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