Responses to crizotinib and chemotherapy in patients with lung adenocarcinoma harboring a concomitant EGFR mutation and ALK gene rearrangement: A case report and review of the literature

Previous studies have indicated that, in lung cancers, the gene rearrangement of ALK is mutually exclusive with mutations in the epidermal growth factor receptor (EGFR) gene. However, the coexistence of EML4-ALK fusions and EGFR mutations (double positive) has been occasionally reported, with freque...

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Detalhes bibliográficos
Publicado no:Mol Clin Oncol
Main Authors: Li, Yuping, Su, Shanshan, Cai, Guoping, Lin, Quan, Zhou, Ying, Ouyang, Jinsheng, Chen, Bicheng, Ye, Junru, Wu, Xiuling, Chen, Chengshui
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532680/
https://ncbi.nlm.nih.gov/pubmed/28781781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mco.2017.1306
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