Intratumoral Heterogeneity of ALK-Rearranged and ALK/EGFR Coaltered Lung Adenocarcinoma

PURPOSE: Genetic intratumoral heterogeneity has a profound influence on the selection of clinical treatment strategies and on addressing resistance to targeted therapy. The purpose of this study was to explore the potential effect of intratumoral heterogeneity on both genetic and pathologic characte...

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Veröffentlicht in:J Clin Oncol
Hauptverfasser: Cai, Weijing, Lin, Dongmei, Wu, Chunyan, Li, Xuefei, Zhao, Chao, Zheng, Limou, Chuai, Shannon, Fei, Ke, Zhou, Caicun, Hirsch, Fred R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770798/
https://ncbi.nlm.nih.gov/pubmed/26416997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.8293
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