Intratumoral Heterogeneity of ALK-Rearranged and ALK/EGFR Coaltered Lung Adenocarcinoma

PURPOSE: Genetic intratumoral heterogeneity has a profound influence on the selection of clinical treatment strategies and on addressing resistance to targeted therapy. The purpose of this study was to explore the potential effect of intratumoral heterogeneity on both genetic and pathologic characte...

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Bibliographic Details
Published in:J Clin Oncol
Main Authors: Cai, Weijing, Lin, Dongmei, Wu, Chunyan, Li, Xuefei, Zhao, Chao, Zheng, Limou, Chuai, Shannon, Fei, Ke, Zhou, Caicun, Hirsch, Fred R.
Format: Artigo
Language:Inglês
Published: American Society of Clinical Oncology 2015
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ORIGINAL REPORTS
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770798/
https://ncbi.nlm.nih.gov/pubmed/26416997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.58.8293
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