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A transcription factor network model explains heterogeneity and reveals a novel hybrid phenotype in Small-Cell Lung Cancer

Small cell lung cancer (SCLC) is a devastating disease because of its tendency to early invasion and refractory relapse after initial treatment response. These aggressive traits have been associated with phenotypic heterogeneity, which however remains incompletely understood. To fill this knowledge...

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Publicado no:Cancer Res
Principais autores: Udyavar, Akshata R., Wooten, David J., Hoeksema, Megan, Bansal, Mukesh, Califano, Andrea, Estrada, Lourdes, Schnell, Santiago, Irish, Jonathan M., Massion, Pierre P., Quaranta, Vito
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532541/
https://ncbi.nlm.nih.gov/pubmed/27932399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1467
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