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Mass-spectrometry analysis of modifications at DNA termini induced by DNA polymerases

Non-natural nucleotide substrates are widely used in the enzymatic synthesis of modified DNA. The terminal activity of polymerases in the presence of modified nucleotides is an important, but poorly characterized, aspect of enzymatic DNA synthesis. Here, we studied different types of polymerase acti...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Smirnov, Igor P., Kolganova, Natalia A., Vasiliskov, Vadim A., Chudinov, Alexander V., Timofeev, Edward N.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532294/
https://ncbi.nlm.nih.gov/pubmed/28751641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06136-9
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