Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells

Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on attachment) through a multi-step end-on conversion process. Upstream regulators that orchestrate this remarkable change in the plane of kinetochore-microtubule attachment in huma...

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Udgivet i:Nat Commun
Main Authors: Shrestha, Roshan L., Conti, Duccio, Tamura, Naoka, Braun, Dominique, Ramalingam, Revathy A., Cieslinski, Konstanty, Ries, Jonas, Draviam, Viji M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5532248/
https://ncbi.nlm.nih.gov/pubmed/28751710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00209-z
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