Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection

Effective CD8 T cell responses are vital for the control of chronic viral infections. Many factors of the host immune response contribute to the maintenance of effector CD8 T cell responses versus CD8 T cell exhaustion during chronic infection. Specific MHC alleles and the degree of MHC heterogeneit...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS Pathog
Prif Awduron: Christiaansen, Allison F., Schmidt, Megan E., Hartwig, Stacey M., Varga, Steven M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2017
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531689/
https://ncbi.nlm.nih.gov/pubmed/28715493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006498
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