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Host genetics play a critical role in controlling CD8 T cell function and lethal immunopathology during chronic viral infection
Effective CD8 T cell responses are vital for the control of chronic viral infections. Many factors of the host immune response contribute to the maintenance of effector CD8 T cell responses versus CD8 T cell exhaustion during chronic infection. Specific MHC alleles and the degree of MHC heterogeneit...
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| Publicado en: | PLoS Pathog |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531689/ https://ncbi.nlm.nih.gov/pubmed/28715493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006498 |
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