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Assisted Design of Antibody and Protein Therapeutics (ADAPT)

Effective biologic therapeutics require binding affinities that are fine-tuned to their disease-related molecular target. The ADAPT (Assisted Design of Antibody and Protein Therapeutics) platform aids in the selection of mutants that improve/modulate the affinity of antibodies and other biologics. I...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Vivcharuk, Victor, Baardsnes, Jason, Deprez, Christophe, Sulea, Traian, Jaramillo, Maria, Corbeil, Christopher R., Mullick, Alaka, Magoon, Joanne, Marcil, Anne, Durocher, Yves, O’Connor-McCourt, Maureen D., Purisima, Enrico O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531539/
https://ncbi.nlm.nih.gov/pubmed/28750054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181490
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