Roles of the low density lipoprotein receptor and related receptors in inhibition of lipoprotein(a) internalization by proprotein convertase subtilisin/kexin type 9

Elevated plasma concentrations of lipoprotein(a) (Lp(a)) are a causal risk factor for cardiovascular disease. The mechanisms underlying Lp(a) clearance from plasma remain unclear, which is an obvious barrier to the development of therapies to specifically lower levels of this lipoprotein. Recently,...

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Bibliographic Details
Published in:PLoS One
Main Authors: Romagnuolo, Rocco, Scipione, Corey A., Marcovina, Santica M., Gemin, Matthew, Seidah, Nabil G., Boffa, Michael B., Koschinsky, Marlys L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531514/
https://ncbi.nlm.nih.gov/pubmed/28750079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180869
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