Generation and phenotypic characterization of Pde1a mutant mice

It has been proposed that a reduction in intracellular calcium causes an increase in intracellular cAMP and PKA activity through stimulation of calcium inhibitable adenylyl cyclase 6 and inhibition of phosphodiesterase 1 (PDE1), the main enzymes generating and degrading cAMP in the distal nephron an...

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Udgivet i:PLoS One
Main Authors: Wang, Xiaofang, Yamada, Satsuki, LaRiviere, Wells B., Ye, Hong, Bakeberg, Jason L., Irazabal, María V., Chebib, Fouad T., van Deursen, Jan, Harris, Peter C., Sussman, Caroline R., Behfar, Atta, Ward, Christopher J., Torres, Vicente E.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531505/
https://ncbi.nlm.nih.gov/pubmed/28750036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181087
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