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DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes
Loss of DNA-dependent protein kinase catalytic subunit (DNA-PKcs) activity in mammals results in severe combined immuno-deficiency (SCID). This SCID phenotype has been postulated to be due solely to the function of DNA-PKcs in V(D)J recombination, a process critical for lymphocyte maturation. Howeve...
Tallennettuna:
| Julkaisussa: | PLoS One |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5531461/ https://ncbi.nlm.nih.gov/pubmed/28750002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181608 |
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