Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

The tumor microenvironment plays an important role in tumor growth and metastasis. However, the mechanism by which tumor cells regulate the cell and non-cell constituents of surrounding stroma remains incompletely understood. Promyelocytic leukemia (PML) is a pleiotropic tumor suppressor, but its ro...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Wang, Ya-Ting, Chen, Jocelyn, Chang, Chou-Wei, Jen, Jayu, Huang, Tzu-Yu, Chen, Chun-Ming, Shen, Roger, Liang, Suh-Yuen, Cheng, I-Cheng, Yang, Shuenn-Chen, Lai, Wu-Wei, Cheng, Kuang-Hung, Hsieh, Tao-Shih, Lai, Ming-Zong, Cheng, Hung-Chi, Wang, Yi-Ching, Chen, Ruey-Hwa
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2017
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531412/
https://ncbi.nlm.nih.gov/pubmed/28691927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI89957
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