Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study

Observational studies have shown an association between obesity and venous thromboembolism (VTE) but it is not known if observed associations are causal, due to reverse causation or confounding bias. We conducted a Mendelian Randomization study of body mass index (BMI) and VTE. We identified 95 sing...

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Published in:Hum Genet
Main Authors: Lindström, Sara, Germain, Marine, Crous-Bou, Marta, Smith, Erin N., Morange, Pierre-Emmanuel, van Hylckama Vlieg, Astrid, de Haan, Hugoline G., Chasman, Daniel, Ridker, Paul, Brody, Jennifer, de Andrade, Mariza, Heit, John A, Tang, Weihong, DeVivo, Immaculata, Grodstein, Francine, Smith, Nicholas L., Tregouet, David, Kabrhel, Christopher
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531049/
https://ncbi.nlm.nih.gov/pubmed/28528403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-017-1811-x
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