Assessing the causal relationship between obesity and venous thromboembolism through a Mendelian Randomization study

Observational studies have shown an association between obesity and venous thromboembolism (VTE) but it is not known if observed associations are causal, due to reverse causation or confounding bias. We conducted a Mendelian Randomization study of body mass index (BMI) and VTE. We identified 95 sing...

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Veröffentlicht in:Hum Genet
Hauptverfasser: Lindström, Sara, Germain, Marine, Crous-Bou, Marta, Smith, Erin N., Morange, Pierre-Emmanuel, van Hylckama Vlieg, Astrid, de Haan, Hugoline G., Chasman, Daniel, Ridker, Paul, Brody, Jennifer, de Andrade, Mariza, Heit, John A, Tang, Weihong, DeVivo, Immaculata, Grodstein, Francine, Smith, Nicholas L., Tregouet, David, Kabrhel, Christopher
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5531049/
https://ncbi.nlm.nih.gov/pubmed/28528403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-017-1811-x
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